An investigation on the pathogenic mechanism and therapeutic strategy of spinocerebellar ataxia type 3

博士 === 長庚大學 === 臨床醫學研究所 === 96 === Spinocerebellar ataxia type 3 (SCA3) is an inherited autosomal dominant neurodegenerative disorder caused by polyglutamine-expanded ataxin-3. In the present study, we prepared in vitro cellular model of SCA3 by expressing mutant polyglutamine atain-3-Q79 in culture...

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Bibliographic Details
Main Authors: An Hsun Chou, 左安順
Other Authors: H. L. Wang
Format: Others
Published: 2008
Online Access:http://ndltd.ncl.edu.tw/handle/794pwc