| Summary: | 碩士 === 臺灣大學 === 應用力學研究所 === 95 === In this study, the gray level B-mode ultrasound image analysis of liver parenchyma and hepatic vein and portal vein Power Doppler Vascular Index (PDVI) analysis was used to differentiate liver cirrhosis. The characteristic parameters extracted from grey-level co-occurrence matrix was statistical significant in differentiating the normal liver and the cirrhotic liver.
The PDVI waveforms measured from hepatic vein is more regular or periodic in the normal livers than in the cirrhotic livers. The ratio of maximum PDVI to minimum PDVI ( PDVImax : PDVImin ) for hepatic vein were 2.44 ± 0.85 in control normal, and 1.52 ± 0.26 in patients with liver cirrhosis, and is statistical significant. ( p = 0.007, with threshold of 1.8, sensitivity 93.75%, specificity 80%). Such a difference of PDVI ratio in the portal vein was not as significant as in the hepatic vein.
The hepatic vein for normal control subjects can be considered as an elastic vessel. When the liver becomes fibrosis, the vessel would lose its elasticity. Therefore, the pulsation of PDVI of blood vessel decreases, and such the difference would be easily detectable in the hepatic vein than the portal vein. Generally, use the PDVI ratio as an clinical index for differentiating normal livers and cirrhotic livers would to be meaningful.
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