Antioxidant Activities and Safety Evaluation of Nano/submicron Lycium spp. suspension

• Main Authors: Ya-Ting Chan, 詹雅婷
• Other Authors: An-I Yeh
• Format: Others
• Language: zh-TW
• Published: 2007
• Online Access: http://ndltd.ncl.edu.tw/handle/12868124442742302418

碩士 === 國立臺灣大學 === 食品科技研究所 === 95 === This study discussed the preparation, antioxidant activities, and safety of nano/submicron Lycium spp.. Media milling was used to reduce the material to nano/submicron scale. After milling for 90min，the volume mean diameter decreased to 15.3μm and the number mean diameter decreased to 102 nm. The volume mean diameter after centrifugation (10000 ×g, 10min) was about 587.5 nm. Transmission electron microscopic (TEM) photographs also proved the existence of nano/submicron scale particle. The reducing power, ferrous chelating effect (EC50=2.11 mg/mL) and the Trolox equivalent antioxidant capacity (TEAC) assay (TEAC value=0.028mM) of milled product is higher than that of hot, cold water and 95% ethanol extract. The total polyphenol (19.3 mg/g) , total carotenoids (1.27 mg/g) and β-carotene (0.23 mg/g) contents in milled product was higher than that in the extract by hot, cold water and 95% ethanol. The flavonoids (4.01 mg/g) in milled product was higher than that in the extract by hot, cold water. From Ames test, nano/submicron Lycium suspension in this study had no mutagenic effect to the Samonella typhimurium TA 98 and TA100.