Quantitative analysis on optical properties of human vessel tissue by using polarization-sensitive optical coherence tomography (PS-OCT)

• Main Authors: Ming-Wei Hsiung, 熊名煒
• Other Authors: Wen-Chuan Kuo
• Format: Others
• Language: zh-TW
• Published: 2007
• Online Access: http://ndltd.ncl.edu.tw/handle/91311075028524116281

碩士 === 國立臺灣師範大學 === 光電科技研究所 === 95 === 　　In this study, we developed an algorithm to extract four different optical parameters including scattering coefficient, anisotropy factor, birefringence coefficient, and fast axis angle from polarization-sensitive optical coherence tomography (PS-OCT) images. Scattering coefficient and anisotropy factor can be used to describe scattering effect and anisotropy characteristic of the sample. Birefringence property represents the difference in tissue refractive index between the birefringent fast and slow axes, while fast axis angle can describe the fibrous arrangement of the fibrous structure in the tissue. First, we use phantom to test and correct our algorithm in this study. And then, we demonstrate that the optical characteristic of normal and different kinds of lesions in human vessel can be quantitative described by this method. In addition, we also discuss the birefringence properties of several different tissues in detail.