| Summary: | 碩士 === 國立清華大學 === 工業工程與工程管理學系 === 95 === Tuberculosis is a chronic infectious disease which endangers the human health for a long time. It is a common disease existing in the whole world at present time, especially in the undeveloped and developing country. If properly cared, the tuberculosis patient can almost be cured. Otherwise, if not taking effective cure method, half of the tuberculosis patient will die in three years. And now the tuberculosis is developed into the mortal case – the drug resistance TB and the prevailing of the TB and AIDS which is a great calamity. The danger of the infectious disease in one country is the important index of testing system of national hygiene. How can we minimize the number of the infectious patients under the limited budget is what we are concerned.
In this thesis, first we add the common case - infection of drug resistance compartment in our epidemic model, and we also consider the transmission rate of transferring from chronic patients to drug resistance case. We provide some preventing method usually used to control tuberculosis, like DOTS and reducing the contact rate…, and so on. Second, we consider different TB situations in different regions. In any one of the regions , when we collect the data and know the distribution of TB patients in each compartment, we can find out the best resource allocation method to control the disease, Finally, we present one example to illustrate the steps how we get the optimal solution by approximating method.
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