Relationships among nutrient intake, periodontal status and glycemic control in type 2 diabetes mellitus.

• Main Authors: Yu-Heng Hsu, 許玉恒
• Other Authors: Shun-Te Huang
• Format: Others
• Language: zh-TW
• Online Access: http://ndltd.ncl.edu.tw/handle/98774856631201266055

碩士 === 高雄醫學大學 === 口腔衛生科學研究所碩士班 === 95 === Background：The relationship between periodontal disease and diabetes mellitus is well established, and studies have shown that diabetes mellitus is the main reason for the worsening of periodontal disease. Nutrient intake may be one of the important factors affecting periodontal disease and diabetes mellitus; however, the relationship between nutrient intake, biochemical examination, and periodontal disease has rarely been discussed. The objective of this investigation was to examine the relationship between nutrient intake, biochemical examination and periodontal status in patients with diabetes mellitus. Method：211 patients with diabetes mellitus were recruited from the Department of Endocrinology in Kaohsiung Medical University Hospital from April to August, 2006. Subjects were divided into two groups; diabetes-well-controlled (DWC) group and diabetes-badly-controlled (DBC) group. Periodontal status was evaluated by the CPITN index, the condition of nutritional intake was evaluated by a 24-hour diet record, and a questionnaire for food frequency as well as supplements. JMP was used for statistical analysis. Results：The results showed that there was a statistically significant association between patients’ periodontal status(Community Periodontal Index of Treatment Needs, CPITN) and diabetes blood sugar control(hemoglobin A1c, A1C) (p=0.0403). Patients with better periodontal status (CPITN≦2) had higher vitamin E α-TE(mg) intake compared with those of poor periodontal status (p=0.0329). Using multiple regression analysis to adjust sex, age, education degree, body mass index(BMI) and kilocalorie. Vitamin Eα-TE intake to divide into 2 groups (＞75 percentile vs ≦75 percentile) for CPITN was change -0.4, the change was statistically significant. Patients in the DWC group had a lower percentage of carbohydrate intake 53.1%, compared with the DBC group 57.2%, the change was statistically significant (p=0.0119), the higher percentage of dietary fat intake and dietary fat intake was 58.4g and 32.5%, compared with the DBC group was 49.4g and 28.5% , the difference was statistically significant (p=0.0069 and p=0.0387, respectively), and the DWC group had higher n-3 fatty acid intake 0.9g compared with the DBC group 0.5g, the difference was statistically significant (p=0.0434). Using multiple regression analysis to adjust sex, age, education degree, BMI and kilocalorie. The carbohydrate and fat per intake to add 10g for A1C of change, the change was statistically significantly different (p=0.0297 and p=0.0484, respectively). N-3 fatty acid intake to divide into 2 groups (＞75 percentile vs ≦75 percentile) for A1C was change, the regression coefficient was a statistically significant difference (p=0.0053). another to accede to adjusting for smoking, alcohol and betel nut, N-3 fatty acid intake to divide into 2 groups for A1C was change, the regression coefficient -1.14 was a statistically significant difference (p=0.0021). Conclusion: These findings diabetes mellitus patient with better periodontal status, higher vitamin E α-TE intake. To adjust kilocalorie, that lower dietary carbohydrate, increase dietary fat intake with lower A1C has correlation; DWC had higher n-3 fatty acid intake. To raise fish intake, especially deep sea of fish frequency of intake, with Total-Cholesterol, Triglyceride and Low density Cholesterol had negative coefficient, the coefficient was a statistically significant difference, that had to reduce the diabetes mellitus patient of cardiovascular diseases hazard factor. So that can protect the cardiovascular system.