| Summary: | 碩士 === 中國醫藥大學 === 護理學系碩士班 === 95 === Yin-deficiency (YD) is common seen in cancer patients under late stage. So far, it is not known whether the Yin-deficient symptoms (YDS) are related to ANS functions which include heart rate variability, basal metabolic rate and blood pressure. The aims of this study were to evaluate the distribution of YDS, to analyze its’ relationships with ANS functions, and to investigate whether YDS and ANS functions can predict the survival time in cancer patients with YD.
A cross sectional and follow-up study was conducted on cancer patients in a teaching hospital in middle Taiwan. Forty-three patients were involved after signature of informed consent. We used a structure questionnaire to evaluate the severities of YDS, and measured ANS function with an analysis system, namely Lab VIEWTM. We also measured blood pressure with a monitor, namely ANS Watch, and further calculated basal metabolic rate with a special formula. We coded the collected questionnaire material and performed Statistics with SPSS12.0 coverall software. Data were analyzed by descriptions analysis, ANOVA, Pearson’s correlation coefficients, t-test, multiple regression and Kaplan Meier methods.
The results revealed that, the most 3 frequent and severe symptoms/signs in cancer patients with YD were poor sleep with annoyance (90.7%) , less or non-coated tongue with or without redness (86.0%), and dry mouth (69.8%). LF power had a significantly negative correlation with the summated degree of poor sleep with annoyance had but significantly positive correlations with both dizziness and rapid- small pulse. Heart rate had a significantly negative correlation with blurring vision but a significantly positive correlation with hot over palm and sole. LF/HF ratio had a significantly positive correlation with tinnitus and hearing decrease. On the other hand, BMR had the significantly positive correlations with both the summated degree of hot over palm and sole and night sweating but a significantly negative correlation with tinnitus and hearing decrease. The analysis on the survival rates of subjects for 4 months revealed that, 5 parameters including increased heart rate, decreased LF power and VLF power, less or non- coated tongue without redness and increased basal metabolic rate can predict the survival rate.
Our study results also suggest that, the evaluation of Yin-deficient symptoms/signs can help medical doctors and nurses to early detect YD and imbalance of ANS in cancer patients and to make proper nursing management as soon as possible. This will increase the quality of nursing care and promote the therapeutic effect.
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