| Summary: | 碩士 === 中國醫藥大學 === 針灸研究所碩士班 === 95 === A number of the studies indicate that there is different physiological mechanism between electroacupuncture (EA) and transcutaneous electrical nerve stimulation (TENS). Therefore, the purpose of the present study was to investigate the effect of EA and TENS at bilateral Zusanli acupoints on median nerve-somatosensory evoked potentials (MN-SEPs) to compare the difference of physiological mechanism between EA and TENS. A total of 20 healthy adults’ volunteers were studied. We used 4 Hz electrical stimulation applied to median nerve of left wrist to obtain SEPs. The electrodes were placed on the skin of 7th cervical spine process to obtain spinal cord potentials N13, on the hand area of right sensory cortex scalp to obtain sensory cortex potentials N20-P25, and obtain the late component N30 and P44, respectively. 2 Hz EA and 2 Hz TENS applied to bilateral Zusanli and Shangjuxu acupoints, respectively. We observed the changes of latencies and amplitudes of N13, N20, P25, N30 and P44 components to compare the effect of EA and TENS on MN-SEPs. Three sessions of sham stimulation (no EA or TENS), 2 Hz EA and 2 Hz TENS were done in each subject. The interval between sessions was at least 7 days, and each session was divided into before acupuncture period, acupuncture period and post acupuncture. MN-SEPs recorded at least two times in each period. The results indicated that 2Hz EA could enhance the N20 and N30 amplitudes of MN-SEPs, but no similar change was found in the 2 Hz TENS and sham acupuncture.
In conclusion, 2Hz EA can enhance the N20 and N30 amplitudes of MN-SEPs, but no similar change was found in the 2 Hz TENS and sham acupuncture, suggesting that there is different effect on cerebral cortex between 2 Hz EA and 2 Hz TENS; 2 Hz EA can not change the latency and amplitude of N13 component, but enhances the amplitude of N20 and N30, suggesting that main physiological mechanism of 2 Hz EA at Zusanli acupoints occur in the cerebral cortex.
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