The analysis of protein interaction network by Network Component Analysis

碩士 === 國立中正大學 === 化學工程所 === 95 === This research is to analyze the data of the cell cycle of Saccharimyces by Network Component Analysis and to understand the regulation of the transcription factors during cell cycle. Although transcription factors depend on much gene, we adopt the Principle Compone...

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Bibliographic Details
Main Authors: Kung-Feng Wang, 王國峰
Other Authors: Feng-sheng Wang
Format: Others
Language:zh-TW
Published: 2007
Online Access:http://ndltd.ncl.edu.tw/handle/77443712707965364762
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Summary:碩士 === 國立中正大學 === 化學工程所 === 95 === This research is to analyze the data of the cell cycle of Saccharimyces by Network Component Analysis and to understand the regulation of the transcription factors during cell cycle. Although transcription factors depend on much gene, we adopt the Principle Component Analysis to get the most important ones. After that, we use the Network Component Analysis to analyze the most important transcription factors. So we can realize the profile of transcription factors changing as necessary and the regulation from the Connectivity Strength. Beside, we adopt the NCA to know the regulation of the Zebrafish system.