The heart rate variability analysis of Irreversible Apneic Coma and brain death via Poincare'' plot

• Main Authors: Bo-Kai Hu, 胡博凱
• Other Authors: Jiann-Shing Shieh
• Format: Others
• Language: zh-TW
• Published: 2006
• Online Access: http://ndltd.ncl.edu.tw/handle/83052802837122301401

碩士 === 元智大學 === 機械工程學系 === 94 === The purpose of this research is to find the heart rate variability (HRV) of irreversible apneic coma (IAC) and brain death for the clinical correlation research. IAC, or the rather controversial term - brain death, is defined as the irreversible loss of function of the brain. Sympathetic storm, a cardiovascular hyperdynamic state occurring in the process of brain stem failure, has been well studied in animal models. Observations of hypertension and tachycardia due to intense vasoconstriction in IAC patients have been described in clinical settings. The phenomenon of sympathetic storm was also mentioned by researchers after introducing the HRV, suggesting its contributory potential to the diagnosis of IAC. The Poincare'' plots are one of the non-linear analysis of HRV. We calculate Poincare'' plot index (SD1, SD2 and area) and frequency index (HF/LF, HF/TF) in order to obtain the relationship between HRV and Autonomic nervous system. Observing the Poincare'' plots of three groups (IAC, normal coma and normal), We find the shapes of IAC and brain death patients are fan and area are smaller, but shapes of normal people are comet and area are bigger. Finally we use statistics to discuss the difference of Poincare'' plots with three groups.