Study on the CDR regions of anti-dsDNA monoclonal autoantibody for antigen-binding by site-directed mutagenesis

碩士 === 國立陽明大學 === 醫學生物技術研究所 === 94 === Autoantibodies against double-stranded DNA (anti-dsDNA) have been detected in patients of systemic lupus erythematosus (SLE). These abnormal antibodies may play an important role in lupus nephritis. The monoclonal anti-dsDNA 9D7 has been demonstrated to penetra...

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Bibliographic Details
Main Authors: Chien-jen Chen, 陳建任
Other Authors: Kuang-Hui Sun
Format: Others
Language:zh-TW
Published: 2006
Online Access:http://ndltd.ncl.edu.tw/handle/47669158772219108452