Effects of supplementation with whey protein on TAE KWON-DO athletes’ kick performance and T lymphocyte functions.

• Main Authors: Chang, Yu Pei, 張玉佩
• Other Authors: Tai-Ger Hsu
• Format: Others
• Language: zh-TW
• Published: 2006
• Online Access: http://ndltd.ncl.edu.tw/handle/12723827147890041782

碩士 === 臺北巿立體育學院 === 運動科學研究所 === 94 === Our country has been actively promoting TAE KWON DO sports for several years. Exercise is hypothesized to induce oxidative stress by a number of biochemical events. Exercise induced increases of metabolism rate and metabolic leak from mitochondrial electron transport chains are now thought to be the most important source of oxygen-derived radicals. The increase in oxygen uptake during exercise is accompanied by an elevation of reactive oxygen species (ROS) leading to oxdative stress. Oxidative stress has contributed to muscule and endurance fatigue. Exercise may also induce inflammatory reactions similar to the acute phase response occurring in injury or infection. Exercise is also associated with various degree of immune disturbance, with its severity depending on the intensity of exercise. T cell plays an important role in the human immune system, not only having the ability to carry on cytolysis function of the cell that suffered from the virus infection, but also having functions of regulating other immunocytes. Whey protein is thought to exert its effects that are by intracellular conversion of the amino acid cysteine to glutathione, a potent intracellular antioxidant. And the change of the GSH concentration can affect the activity of the T cell. We had investigated the effects of supplementation with whey protein on exercise performance, glutathione concentration, and T cell activity. Twenty-four distance running athletes were participated in this study. Pre-supplementation and 4 weeks post-supplementation with either Immunocal (20g/day) or none were studied. After dietary supplementation with whey protein, slightly increases in muscle ratio and muscle endurance were found, but not significantly. For the immune function part, the TH and TC cell counts and activities were both increased (p < .05). And the cytokine IFN-γ and IL-10 producing cells were significant reduced. In conclusion, after 4 weeks of supplementation with whey protein, the lymphocyte surface GSH concentration was raised, and TH cell and TC cell count and activity were stimulated. However, the numbers of INF-γ and IL-4 or IL-10 producing TH1 and TH2 cells respectively were both decreased under the higher concentration of GSH indicating that the effects of dietary whey protein supplementation on the immunological status of human can not be assessed only by a few kind cytokines production and thus need further investigation.