2-Amino and 2’-Aminocombretastatins Derivatives as Potent Antimitotic Agents
碩士 === 臺北醫學大學 === 藥學系 === 94 === A novel series of 2-amino and 2’-aminocombretastatins derivatives was synthesized and evaluated for antitumor activity. Several compounds had excellent antiproliferative activity as inhibitors of tubulin polymerization. Compound 1, 11, and 12 with IC50 of 1.6, 1...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2006
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| Online Access: | http://ndltd.ncl.edu.tw/handle/56495780464339932541 |