| Summary: | 碩士 === 國立臺灣大學 === 臨床牙醫學研究所 === 94 === Chapter 1 Availability of fluoride in fluoridated milk
The nutrients supplied by milk are essential components of the human diet throughout life, especially for babies and young children. From mid-1950, several papers were published concerning the possible use of fluoridated milk as a dental caries preventive measure for children. However, some scientists questioned the suitability of using milk as a vehicle for fluoride, claiming that ionic fluoride interacts with milk constituents and, as a result would be irretrievably lost in the milk. The purpose of this study was to know the availability of fluoride ion after adding to milk. Exact same amount of NaF powder was dissolved into distilled water and milk. Fluoride electrode was used to measure and compare the ionic concentration of the samples . The results show : 1) In higher concentration of fluoridated milk (250-1000 ppm) , the availability of fluoride is about 68% to 83%. In lower concentration of fluoridated milk(0.19-19 ppm), the availability is about 35% to 65%. The higher the concentration, the higher the availability 3) To compare with different kinds of milk, the availability of fluoride is the highest in full milk, the lowest in the milk with lower-fat and higher calcium. In conclusion, although fluoride will bind with the components of milk when adding into milk , there are still available fluoride in fluoridated milk. The availability of fluoride in fluoridated skim with high calcium milk was lower than full milk and baby formula.
Chpater 2 Effect of fluoridated milk on demineralization of human enamel
The anti-caries effects of fluoride are primarily topical rather than systemic benefits. Although fluoride will bind with the components of milk when adding into milk , there are still available fluoride in fluoridated milk. Therefore, the amount of available fluoride is efficient for prevention of dental caries. The purpose of this study was to investigate the effect of milk and fluoridated milk on enamel caries formation in vitro. We compare the size of artificial caries-like lesions created in demineralization solution (DS), acidified milk, acidified 5 ppm fluoridated milk with the in vitro method of continuous demineralization (n=39) and pH-cycling (n=28). The results show that : 1) in the model of continuous demineralization (n=39), 100%, 48.7% and 33.3% of the specimen in respective group produced lesions. 2) in the model of pH-cycling (n=28), 100%, 60.7% and 32.1% of the specimen in respective group produced lesions. The depth of artificial lesions created most with DS, least with acidified fluoridated milk in both experiments. It seems that milk may have anti-caries effect, because the number of caries-like lesions and the depth of the artificial lesions created in milk were less than those in DS. The number of caries-like lesions and the depth of the artificial lesions created least with acidified fluoridated milk. It implied that the fluoridated milk can be used for the purpose of preventing dental caries.
|
|---|
