Synthesis and structural analysis of mutant K+ channel blocker Tc32, from the Scorpion Tityus cambridgei

Synthesis and structural analysis of mutant K+ channel blocker Tc32, from the Scorpion Tityus cambridgei

碩士 === 國立臺灣大學 === 生化科學研究所 === 94 === Tc32 is a K+ channel-blocking peptide purified from the venom of Amazonian scorpion Tityus cambridgei and composed of 35 amino acid residues (TGPQT- TCQAA-MCEAG-CKGLG-KSMES-CQGDT-CKCKA) cross linked with three disulfide bridges. Tc32 is classified as the first nu...

Full description

Bibliographic Details
Main Authors:	Sho-Fine Chang, 張修桓
Other Authors:	Shih-Hsiung Wu
Format:	Others
Language:	en_US
Published:	2006
Online Access:	http://ndltd.ncl.edu.tw/handle/13845450994390878408

Similar Items

Structural studies of the K+ Channel Blocker Tc32 from the Scorpion Tityus cambridgei
by: I-Che Huang, et al.
Published: (2004)

Structural studies of the K+ Channel Blocker Tc32,from the Scorpion Tityus cambridgei
by: I-Che Huang, et al.
Published: (2004)

Identification and phylogenetic analysis of Tityus pachyurus and Tityus obscurus novel putative Na+-channel scorpion toxins.
by: Jimmy A Guerrero-Vargas, et al.
Published: (2012-01-01)

Scorpionism by Tityus silvestris in eastern Brazilian Amazon
by: Johne Souza Coelho, et al.
Published: (2016-09-01)

Primeiro registro de escorpionismo causado por Tityus adrianoi Lourenço (Scorpiones: Buthidae) First record of scorpionism caused by Tityus adrianoi Lourenço (Scorpiones: Buthidae)
by: Éder Sandro Soares Álvares, et al.
Published: (2006-08-01)

Envenenamento por Tityus stigmurus (Scorpiones; Buthidae) no Estado da Bahia, Brasil Envenomation by Tityus stigmurus (Scorpiones; Buthidae) in Bahia, Brazil
by: Rejâne Maria Lira-da-Silva, et al.
Published: (2000-06-01)

Escorpionismo por Tityus pusillus Pocock, 1893 (Scorpiones; Buthidae) no Estado de Pernambuco Scorpionism caused by Tityus pusillus Pocock, 1893 (Scorpiones; Buthidae) in State of Pernambuco
by: Cleide Maria Ribeiro de Albuquerque, et al.
Published: (2009-04-01)

THE MOUSE AS AN EXPERIMENTAL MODEL FOR TITYUS SERRULATUS SCORPION ENVENOMING
by: Mônica de Mônico Magalhães, et al.
Published: (1998-10-01)

Scorpionism due to Tityus neoespartanus (Scorpiones, Buthidae) in Margarita Island, northeastern Venezuela Escorpionismo por Tityus neoespartanus (Scorpiones, Buthidae) na Ilha de Margarita, Nordeste da Venezuela
by: Leonardo De Sousa, et al.
Published: (2007-12-01)

Selection of environmental temperature by the yellow scorpion Tityus serrulatus Lutz & Mello, 1922 (Scorpiones, Buthidae)
by: K. Hoshino, et al.
Published: (2006-01-01)

Selected to survive and kill: Tityus serrulatus, the Brazilian yellow scorpion.
by: Ricardo José Gonzaga Pimenta, et al.
Published: (2019-01-01)

Embriotoxic effects of maternal exposure to Tityus serrulatus scorpion venom
by: A. A. S. Barão, et al.
Published: (2008-01-01)

Mild reproductive effects of the Tityus bahiensis scorpion venom in rats
by: Ana Leticia C Dorce, et al.
Published: (2014-02-01)

Immunomodulatory activity of Tityus serrulatus scorpion venom on human T lymphocytes
by: Andrea Casella-Martins, et al.
Published: (2015-12-01)

Meiosis in the scorpion Tityus silvestris: new insights into achiasmatic chromosomes
by: Bruno Rafael Ribeiro de Almeida, et al.
Published: (2019-05-01)

Description of the male of Tityus kuryi Lourenço, 1997 and notes about males of Tityus stigmurus (Thorell, 1877) and Tityus serrulatus Lutz & Mello, 1922 (Scorpiones, Buthidae)
by: Maria Dulcineia dos Santos, et al.
Published: (2014-08-01)

Nueva especie de Tityus (Scorpiones: Buthidae) del Turimiquire, Venezuela
by: Leonardo De Sousa, et al.
Published: (2006-06-01)

Primer registro de Tityus trivittatus (Scorpiones: Buthidae) en la provincia de Mendoza (Argentina) First record of Tityus trivittatus (Scorpiones: Buthidae) in Mendoza province (Argentina)
by: Florencia Fernández Campón, et al.
Published: (2009-06-01)

<b>Growth and developmental time in the parthenogenetic scorpion <i>Tityus stigmurus</i> (Thorell, 1876) (Scorpiones: Buthidae)
by: Adriano Medeiros de Souza, et al.
Published: (2016-07-01)

Maintenance of scorpions of the genus Tityus Koch (Scorpiones, Buthidae) for venom obtention at Instituto Butantan, São Paulo, Brazil
by: D. M. Candido, et al.
Published: (2004-01-01)

Tityus stigmurus (Thorell, 1876) (Scorpiones; Buthidae): response to chemical control and understanding of scorpionism among the population Tityus stigmurus (Thorell, 1876) (Scorpiones; Buthidae): resposta ao controle químico e entendimento da população sobre escorpionismo
by: Cleide Maria Ribeiro de Albuquerque, et al.
Published: (2009-06-01)

A comparative study of severe scorpion envenomation in children caused by Tityus bahiensis and Tityus serrulatus Estudo comparativo do envenenamento escorpiônico grave em crianças provocado por Tityus bahiensis e Tityus serrulatus
by: Fábio Bucaretchi, et al.
Published: (1995-08-01)

Karyotype diversity and chromosomal organization of repetitive DNA in Tityus obscurus (Scorpiones, Buthidae)
by: Bruno Rafael Ribeiro de Almeida, et al.
Published: (2017-04-01)

Aspects toxinológics, clinical and epidemiological of the poisoning produced by the scorpionTityus fuhrmanni Kraepelin
by: Abel Díaz Cadavid, et al.
Published: (2002-12-01)

Second record of Tityus bahiensis (Scorpiones, Buthidae) from Venezuela: epidemiological implications
by: L. De Sousa, et al.
Published: (2008-01-01)

Natural occurrence of the Fusarium solani on Tityus stigmurus (Thorell, 1876) (Scorpiones: Buthidae)
by: PL. Santana-Neto, et al.

Age effects on the pharmacokinetics of tityustoxin from Tityus serrulatus scorpion venom in rats
by: E.A. Nunan, et al.
Published: (2004-03-01)

Tityus serrulatus Scorpion Venom Induces Apoptosis in Cervical Cancer Cell Lines
by: Emanuelly Bernardes-Oliveira, et al.
Published: (2019-01-01)

Pediatric epidemiological aspects of scorpionism and report on fatal cases from Tityus stigmurus stings (Scorpiones: Buthidae) in State of Pernambuco, Brazil
by: Cleide Maria Ribeiro de Albuquerque, et al.
Published: (2013-08-01)

The remarkable scorpion diversity in the Ecuadorian Andes and description of a new species of Tityus C. L. Koch, 1836 (Scorpiones, Buthidae)
by: Wilson Lourenco, et al.
Published: (2013-06-01)

Profiling the resting venom gland of the scorpion <it>Tityus stigmurus</it> through a transcriptomic survey
by: Almeida Diego D, et al.
Published: (2012-08-01)

Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions.
by: Ursula Castro de Oliveira, et al.
Published: (2018-01-01)

Tityus serrulatus Scorpion Venom: In Vitro Tests and Their Correlation with In Vivo Lethal Dose Assay
by: Daniela Cajado-Carvalho, et al.
Published: (2017-11-01)

Comments on Environmental and Sanitary Aspects of the Scorpionism by Tityus trivittatus in Buenos Aires City, Argentina
by: Adolfo Rafael de Roodt
Published: (2014-04-01)

The first report of Tityus (Scorpiones: Buthidae) in Anzoátegui State, Venezuela: a new species
by: M. Quiroga, et al.
Published: (2004-01-01)

Identification, molecular and functional analysis of bioactive peptides from the venom of the scorpion, Tityus serrulatus
by: Guo, Xiaoxiao
Published: (2013)

Implication of Tityus apiacas (Lourenco, 2002) in scorpion envenomations in the Southern Amazon border, Brazil
by: Bruna Andressa Jung da Silva, et al.

Notes and observations on courtship and mating in Tityus (Atreus) magnimanus Pocock, 1897 (Scorpiones: Buthidae)
by: LK Ross
Published: (2009-01-01)

Scorpions from the primeval subgenus Archaeotityus produce putative homologs of Tityus serrulatus toxins active on voltage-gated sodium channels
by: A Borges, et al.
Published: (2012-01-01)

Prey detection by two species of neotropical theraphosids, Avicularia avicularia, L and Psalmopoeus cambridgei (Pocock)
by: Ruthven, J. W.
Published: (1987)