| Summary: | 碩士 === 國立彰化師範大學 === 應用運動科學研究所 === 94 === Purpose: To investigate the effects of road race for elite cyclists on antioxidant capacity and muscle damage. Methods: Ten elite cyclists (age =21.4 ± 1.9 years、height =164.4 ± 2.1 cm、body mass =57.6 ± 2.9 kg、body mass index (BMI) =21.2 ± 0.6 kg/m2 ) were recruited during the 2005 National Cycling Road Race Championship. They spent 175.7 ± 4.5 min (7-Km time trial：11.8 ± 0.3 min and 100-Km road race：163.4 ± 4.3 min) to finish the race. The blood samples were collected 2 hours before the race (pre), immediately after the race(0 h), 3, 7, 24, 72, and 120 hours after the race to determine superoxide dismutase (SOD), total glutathione (TGSH), oxidized glutathione (GSSG), creatine kinase (CK), lactate dehydrogenase (LDH), malondialdehyde (MDA), protein carbonyls (PC), uric acid (UA), and nitric oxide (NO). Results: The plasma CK increased 93.66% and 91.08% significantly at 3 and 7 hours after race and the plasma LDH was significantly increased 82.72% and 66.29% at 7 and 24 hours after race as compared to pre. Meanwhile, the TGSH of erythrocyte was significantly elevated 202.92%, 185.71%, and 185.50% at 7, 24, and 72 hours post race. The GSSG of erythrocyte was significantly elevated 125.57%, 160.66%, 195.36%, and 115.07% at 3, 7, 72, and 120 hours post race. No significant changes were found the SOD of erythrocyte and the plasma UA, NO, and MDA. Plasma PC was a marker of protein oxidative damage, decreased 56.10%, 48.44%, and 46.01% significantly at 7, 24, and 72 hours post race. Conclusion: A road race may induce endogenous antioxidant production and muscle damage. High intensity exercise induces oxidative stress, but there is no evidence that this affects sports performance in the short term. In this study, we hope that this information may contribute to understand oxidative stress and muscle damages caused by strenuous exercise. The coaches can be inspired to set up the proper training model to promote sports performance. Moreover, this information may also contribute to set up antioxidants supplement or nutrition plans.
|
|---|
