| Summary: | 碩士 === 中原大學 === 醫學工程研究所 === 94 === The blood pressure of spinal cord injury (SCI) patients with orthostatic syncope phenomenon was changed rapidly within short time during tilt table training and treating. In this research, the pulse arrival time (PAT) and intermittent calibration were estimated by continuous blood pressure (CBP) method of W. Chen, and observed the blood pressure changing during symptomatic. The levels of presyncope symptoms (PS) which included PS 1, 2, 3, and 4 were used to quantify the syncope levels, and evaluate.
In this research, 11 subjects who were in intensive care unit of hospital were used to acquire their physiological signals of invasive blood pressure, noninvasive blood pressure (NBP) etc., and to evaluate the feasibility of CBP method. In addition, 14 normal subjects were used to compare the pulse wave signal between photoplethysmography (PLETH) and cuff measurement.
Then the physiological signals were acquired during the tilt table training. The tilt angles were set at 0, 30, 45, 60 and 75 degree from 9 spinal cord injury patients with symptomatic and asymptomatic. The CBP from pulse wave signal of cuff measurement and NBP were calculated, and compared the levels of PS between CBP and NBP.
In result, the correlation coefficient between CBP and invasive blood pressure was 0.83., and the CBP method between PLETH and cuff measurement was 0.88. It was significant differences between symptomatic and asymptomatic in NBP method, and among the levels of PS in CBP method.
In conclusion, the estimated continuous blood pressure method could verify the discrimination of the levels of PS effectively, and provide the capability of identification of presyncope compared with NBP method.
In the future, the CBP method may provide more information of blood pressure for biofeedback control of orthostatic syncope and make the criterion of reference indicator of presyncope prediction in symptomatic situation.
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