Effects of 8-week neuromuscular electric stimulation training on fatigue in patients with multiple sclerosis

• Main Authors: shin man chen, 陳昕蔓
• Other Authors: 張雅如
• Format: Others
• Language: zh-TW
• Published: 2006
• Online Access: http://ndltd.ncl.edu.tw/handle/03112046433227040000

碩士 === 長庚大學 === 復健科學研究所 === 94 === Multiple sclerosis（MS）is a chronic demyelinating disease of the central nervous system. A common symptom in individual with MS is fatigue. The source of fatigue in individuals with MS is reported to be central originated. In chronic patients with MS, peripheral weakness may result in more peripheral fatigue and worsen the central fatigue. The purpose of this study is to investigate the effect of using neuromuscular electrical stimulation (NMES) training on various components of fatigue in individuals with MS. Nine individuals with MS participated 8-week NMES training on the quadriceps muscle. Maximal voluntary contraction (MVC), voluntary activation (VA), twitch force (TW), general fatigue index, central fatigue index, peripheral fatigue index and Modified fatigue impact scale (MFIS) were tested before and after training. We found that VA, general fatigue index, central fatigue index and MFIS were improved, but muscle strength and peripheral fatigue index were not. We conclude that 8-week NMES training significantly reduce general and central fatigue in individuals with MS.