| Summary: | 碩士 === 國立中正大學 === 心理學所 === 94 === ABSTRACT
It has been shown that the hepatic branch of the vagus nerve innervates the rostral intestine, especially the duodenum. However, our recent tracing has shown that the duodenum has received two other projection pathways from sub-branches of the anterior and posterior gastric branches of the vagus nerves. In order to survey the distribution pattern and the numbers of intraganglionic laminar endings (IGLEs) of three different vagal branches that innervate the duodenum, subdiaphragmatic vagotomy was performed in each subject (Male Sprague-Dawley, 170~270 g, N=5 for each group) and the neural tracer WGA-HRP (0.5~0.8μ) was then injected into the left or right nodose ganglion. A new HRP en bloc process protocol was used to examine the finer branches of the vagus nerve. The hepatic branch innervates the duodenum via the hepato-duodenal branch (also termed as gastroduodenal branch in the literature) and has the densest fibers distributed in both the dorso-ventral and rostro-caudal extensions of the first four centimeter segment of the duodenum. Both gastric branches have two sub-branches (the real “gastro-duodenal” branches) innervate the duodenum via different routs: one follows the lesser curvature and joins the hepato-duodenal branch to innervate the duodenum and the other reaches the duodenum by curving either through the mid-pylorus or the pyloric region close to the greater curvature after branching out from the gastric branch. Moreover, the anterior and posterior “gastro-duodenal” branches respectively innervate mainly the ventral and dorsal parts of the duodenum and both have more fibers in the rostral region and less in the caudal part. With posteriori comparisons, in the 1st centimeter segment of the duodenum, the anterior gastro-duodenal branch has significantly (P < .05) more IGLEs; while in the 3rd and 4th centimeters, the hepatic branch has significantly (P < .05) more IGLEs. In the 2nd centimeter of the duodenum, no statistical difference was found in the numbers of IGLEs among the branches.
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