| Summary: | 碩士 === 國立陽明大學 === 醫學工程研究所 === 93 === Osteoarthritis and Osteoporosis are tow of the most common disease in elders. Because these two diseases won’t happen in patient at the same time, we would like to confer the phenomenon in biomechanical point. Will the different biomechanical properties in femoral neck result in different pathological changes.
Our research will establish finite element model of osteoarthritis and osteoporosis femoral neck trabecular bone, and calculate the index. We’ll also use the relationship between density and material properties to find the subject’s stiffness, and then to calculate the tissue level material properties. Using the real material properties to simulate the compression test and observe the distribution of yield strain. We’ll find out the effect of trbecular index and the material properties on its distribution of yield strain.
The trabecular Young’s modulus we calculate in finite element method are about OA I：16.78 GPa; OA II：17.17 GPa; OP I：10.19 GPa; OP II：12.71 GPa.
The higher the volume fraction, the lower the proportion of yield strain is. There is no significant relation between relative bone surface and its proportion of yield strain. The trabecular thickness seems not related to the proportion. The higher the trabecular number, the stronger the bone is. And the higher the trabecular separation, the weaker the bone is.
If the material properties of bone higher, its distribution of yield strain is lower, no matter the stiffness, shear modulus, or the tissue level Young’s modulus.
Now we know that the material properties affect the trabecular bone more than its geometry. In the other hand, geometry is one of the factors affect material properties much. It can be confer in later study.
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