An association study on obesity and risk factors of atherosclerosis in Kuangfu Amis in Hulien County

• Main Authors: Hsi Chin Chang, 張錫金
• Other Authors: Li Yu Wang
• Format: Others
• Language: zh-TW
• Published: 2004
• Online Access: http://ndltd.ncl.edu.tw/handle/18938365201271377730

碩士 === 慈濟大學 === 原住民健康研究所 === 93 === Abstract Obesity is a very common morbidity for most developed countries. Results of the National Health Examination Survey in Taiwan, which was conducted in 1993-1996, showed that eastern and aboriginal townships had the highest prevalence rates of obesity. Previous studies also demonstrated that obesity, diabetes, hypertension, hyperlipidemia and metabolic syndrome were well-established risk factors of coronary artery disease. The etiology of coronary heart disease in Taiwanese aborigines had never been explored. Therefore, we will carry out a community- based cross sectional study to investigate the relationship between obesity and risk factors of coronary heart disease. Study subject will be selected from residents in Kuangfu township. Informations associated with socio-demographic characteristics, habits of cigarette smoking and alcohol drinking, personal and family history of major diseases, and consumption frequencies of major dietary food items will be obtained by a structured questionnaire interview. A blood samples after 10 hours of fasting will be drawn from all participants for the measurements of fasting plasma glucose, total cholesterol, triglyceride, HDL, LDL and insuline. An anthropometric measurement for all study subjects will be performed by two well-trained nurses.The prevalence of metabolic syndrome were 26.1% 、 37.8% for male and female respectily. After adjustment for age, gender, smoke status, physical activity, obesity or abdominal obesity was associated with significant higher hypertension, diabetes mellitus, hypertriglyceridemia, lower HDL, LDL, metabolic syndrome, hyperinsulinemia and coronary artery disease.After adjustment of age, genter, smoke status and income, increase BMI, waist circumference, adiposity, insuline, uric acid and cholesterol/high density lipoprotein ratio had significiant higher risk of coronary heart disease. Compared nonabdominal obesity with normouricemia, hyperuricemia waist phenotype had significant higher risk of coronary heart disease (OR:24.4, 95% CI:2.88-206.21). We conclude that abdominal obesity had significiant higher risk of hypertention, diabetes, hperlipidemia, hyperinsulinemia, metabolic syndrome and coronary heart disease. Key word: obesity, coronary heart disease, metabolic syndrome, risk factor