| Summary: | 碩士 === 國立臺灣大學 === 應用力學研究所 === 93 === One of the most important development in micro total analysis system (µTAS) is applications of rapid test chip in several aspects like biomedical examines, pathology analysis, and chemical constituent detection. It’s a pressing demand to design a clinical test chip with the advantage of accuracy, rapid, and cheap.
Red blood cells (RBC) shuttle through the close, numerous vessel networks among human bodies and deform shape when getting past blood capillaries. It is found that many diseases affect the elasticity and deformability of RBC. This study makes use of RBC deformable elasticity and introduces an effective micro-fluidic-system composed of high-compatible, high-transparent, and high-stable Polydimethylsiloxane (PDMS) in blood capillaries scale to observe RBC deformations and effects of channel geometry.
After setting up normal RBC experimental data, we attempt to develop a rapid test chip capable of distinguishing RBC ill or not.
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