Assessment of the Potential Medication Safety Risks for Inpatients with Nasogastric Tube Feeding of Enteral Nutrition

• Main Authors: Li-Chai Chen, 陳立材
• Other Authors: Yung-jin Lee
• Format: Others
• Language: zh-TW
• Published: 2005
• Online Access: http://ndltd.ncl.edu.tw/handle/24349298597587018019

碩士 === 高雄醫學大學 === 藥學研究所碩士在職專班 === 93 === Currently, there is no commercially available oral dosage form for tube feeding patients, it has the potential to cause undesirable effects or incompatibilities when instead of taking ordinary dosage orally by crushing destroys to via tube feeding administration and combined with enteral feeding formulas; however, tube obstruction, increased toxicity, or reduced efficacy may occur if an improper administration method is used. Then, it may increase medical costs of hospital. The purpose of this study was to survey medical safety risk prevalence for inpatient that received enteral nutrition through medication with nasogastric tube feeding. To collect all drug profiles for all inpatients who have received enteral nutritions and medications with nasogastric tube feeding in a regional teaching hospital between Jan. to Dec. in 2004. It included 875 patients with 25,680 medication contents for evaluation, and makes a review of assessment of prescriptions. The categories of evaluation were: (1) pharmaceutical incompatibilities, (2) special medication via feeding tube, (3) clogged feeding tube, (4) PVC adsorption with medication, (5) drug- nutrient interactions, and (6) the risks of dangers to medical personnel. This study discovered that total amount of potential medication safety risks was 1,876 and the overall prevalence was 7.3%. The items of results depending on categorizes of evaluation, ward, medical specialty, diagnosis and pharmacology were as follows: The highest prevalence is pharmaceutical incompatibilities which is 4.7%. The highest prevalence was general ward which is 4.3%. The highest prevalence was pulmonary disease which is 2.5%. The highest prevalence was acute respiratory failure which is 3.0%. The highest prevalence was cathartics and laxatives which is 1.6%. Most inpatients using enteral tube feeding are critical and medication complexities. The medication safety for those patients is urgent and need to be emphasized.