A Molecular Approach to Study the Patients with Hyper IgM Syndrome Characterized by Defective Class Switch Recombination

博士 === 長庚大學 === 臨床醫學研究所 === 93 === The production of high-affinity antibody of a class-switch-recombination (CSR) specific isotype and somatic hypermutation (SHM) are orchestrated by the CD40L driven CD40 signaling pathway. Humans with the Hyper IgM syndrome (HIGM) characterized by recurrent infecti...

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Bibliographic Details
Main Authors: Wen-I Lee, 李文益
Other Authors: Ming-Ling Kuo
Format: Others
Language:zh-TW
Published: 2005
Online Access:http://ndltd.ncl.edu.tw/handle/35148077284388202979