PROJECTION FROM PARAVERTEBRAL CHAINS TO CELIAC AND SUPERIOR MESENTERIC GANGLIA

• Main Authors: Chien-Ho Jui, 簡賀瑞
• Other Authors: Feng Bin Wang
• Format: Others
• Language: en_US
• Published: 2005
• Online Access: http://ndltd.ncl.edu.tw/handle/35328459773563299149

碩士 === 國立中正大學 === 心理學所 === 93 === The sympathetic system consists of efferent neurons that innervate the viscera. Pathways issuing from the para- and pre-vertebral ganglia to the gastrointestinal tract have been well established. Clinically, thoracic and splanchnic sympathectomies have been used respectively as a treatment to control the hyperhidrosis and visceral pain that originates from chronic pancreatitis and pancreatic carcinoma. However, little is known on the connection between the paravertebral and prevertebral ganglia. Male Sprague-Dawley rats were injected with the WGA-HRP into the celiac (CG, N=6) or superior mesenteric ganglia (SMG, N=6) to retrogradely trace neurons in the paravertebral ganglia. Three days later, both sides of the sympathetic trunks, including stellate (SG), paravertebral chains (T4-T11), splanchnic (SPL), celiac, and superior mesenteric ganglia, were reserved for the HRP-TMB reaction. After tracer injection, neurons were labeled bilaterally in all of the sympathetic ganglia from the SPL up to the SG and mainly found in the stellate, T11, and splanchnic ganglia. The average numbers of neurons labeled in each sympathetic ganglion after ganglion (CG, SMG) injection were: SPL (273±19, 336±15), T11 (258±16, 216±24), T10 (31.6±3.5, 42.2±6.2), T9 (26±1.7, 19.2±3.4), T8 (11.2±1.2, 11.7±1.0), T7 (9.4±1.3, 7.8±1.2), T6 (5.8±0.8, 4.0±0.6), T5 (2.4±0.5, 1.3±0.5), T4 (0.9±0.3, 0.4±0.2), and SG (681±33, 582±25). The fact that numerous neurons project axons from the rostral sympathetic ganglia, bypass the caudal celiac and superior mesenteric ganglia, and presumably reach the abdominal viscera raises the assessment requirement for the side effects of the thoracic or splanchnic sympathectomy. Furthermore, neurons that project from the stellate ganglion to the abdominal viscera may play a role in shuffling the blood volumes between the abdomen and the limbs in the emergent conditions.