Effect of Ionic Species and Ionic Strength on the Electrophoretic Mobility and Zeta Potential of Bovine Knee Chondrocytes, MMA-SPM, PBCA and SLN

• Main Authors: Da Wei Lin, 林大維
• Other Authors: Yung Chih Kuo
• Format: Others
• Language: zh-TW
• Published: 2005
• Online Access: http://ndltd.ncl.edu.tw/handle/75836931569327093861

碩士 === 國立中正大學 === 化學工程研究所 === 93 === The electrophoretic behavior of articular chondrocytes, solid lipid nanoparticles (SLN), methylmethacrylate-sulfopropylmethacrylate (MMA-SPM) and polybutylcyanoacrylate (PBCA) nanoparticles are investigated in this study. In particular, the effect of ionic species and ionic strength on the electrophoretic mobility and zeta potential of cells and nanoparticles are examined both experimentally and theoretically. On the other hand, SLN was synthesized by emulsion polymerization under various kinds of rotational speed, and observed with FE-SEM. The results show that electrophoretic mobility, zeta potential and fixed surface charge density of chondrocytes, MMA-SPM, PBCA and SLN decreased in absolute value as the ionic strength of the medium increased, and ionic species effect in proper order: Na+ > K+ > Ca2+. The diameter of SLN increases with the rotational speed but drops, is observed its appearance by field emission scanning electron microscope (FE-SEM) and found that the particle surface of SLN is non- level and smooth in addition.