| Summary: | 碩士 === 國立政治大學 === 統計研究所 === 92 === As more medicines are being developed to cope with diseases, most of the users think of the therapeutic effect of the medicine without thinking of the risk that might have associated with drug interactions. The risk of drug interactions could have set chemical reactions thereby causing drug side effects. Although the National Bureau of Controlled Drugs has set a procedure for controlling drug interactions, the issue of validity and efficiency remains an open question.
The trend of people contracting chronic diseases is on the rise, one of which is cardiovascular. The attempt of this paper is to observe for the effect of drug interactions if any for the long term usage of the cardiovascular medications under the supervision of the doctors. We adopt data mining techniques to single out the probable variable causes in triggering negative effect of drug interactions and presented them to related medical personnel so that a tightening measure is adopted when administered the medications. The data used in this research comes from the National Health Insurance Research Database.
Our research findings have reviewed that cardiovascular disease patients suffering from the complications, such as diabetes, arthritis, peptic ulcer and hear disease are highly related to the drug interactions. Heart disease patients are at risk of cardiac stimultants and diuretics. Diabetic’s patients taking the Sulfonylureas suffer from its interactions. And arthritis patients are at risk of having the side effects of taking Aspirin.
Bureau of National Health Insurance should set a standard procedure in monitoring the prescription given by the medical personnel in an effort to reduce the risk of drug interactions and set off the stage of quality medical treatment to keep off the abuse of drug usages.
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