Electrophilic Induced Cyclization of Methyl 2-(6-substitued 3-hexen-1,5-diynyl)benzoate :Synthesis ofIsocoumarins

Electrophilic Induced Cyclization of Methyl 2-(6-substitued 3-hexen-1,5-diynyl)benzoate :Synthesis ofIsocoumarins

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碩士 === 高雄醫學大學 === 藥學研究所碩士在職專班 === 92 === Treatment of methyl 2-(6-substitued 3(Z)-hexen-1,5-diynyl) benzoates with four equivalent of iodine in CH2Cl2 at room temperature gave 4-iodo-3-((1E,3E)-4-substituted-3,4-diiodo-1,3-butadienyl)isocou- marins in 47- 68 % yields. When the amount of iodine was r...

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Main Authors: Tsung-hui Kuo, 郭宗輝
Other Authors: Ming-Jung Wu
Format: Others
Language:zh-TW
Published: 2004
Online Access:http://ndltd.ncl.edu.tw/handle/84913048776455415353
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spelling ndltd-TW-092KMC055510472016-01-04T04:09:34Z http://ndltd.ncl.edu.tw/handle/84913048776455415353 Electrophilic Induced Cyclization of Methyl 2-(6-substitued 3-hexen-1,5-diynyl)benzoate :Synthesis ofIsocoumarins 2-(6-取代基-3-己烯-1,5-二炔基)苯甲酸甲酯的親電性誘導環化：異薫草素的合成 Tsung-hui Kuo 郭宗輝 碩士 高雄醫學大學 藥學研究所碩士在職專班 92 Treatment of methyl 2-(6-substitued 3(Z)-hexen-1,5-diynyl) benzoates with four equivalent of iodine in CH2Cl2 at room temperature gave 4-iodo-3-((1E,3E)-4-substituted-3,4-diiodo-1,3-butadienyl)isocou- marins in 47- 68 % yields. When the amount of iodine was reduced to one equivalent, the reaction gave 4-iodo-3-((E)-4-substituted-1-buten-3-ynyl) isocoumarins in 57- 67 % yields. Other iodinating agents are also introduced in this reaction, similar results were observed when ICl and NIS were employed in this reaction. Ming-Jung Wu 吳明忠 2004 學位論文 ; thesis 74 zh-TW
collection NDLTD
language zh-TW
format Others
sources NDLTD
description 碩士 === 高雄醫學大學 === 藥學研究所碩士在職專班 === 92 === Treatment of methyl 2-(6-substitued 3(Z)-hexen-1,5-diynyl) benzoates with four equivalent of iodine in CH2Cl2 at room temperature gave 4-iodo-3-((1E,3E)-4-substituted-3,4-diiodo-1,3-butadienyl)isocou- marins in 47- 68 % yields. When the amount of iodine was reduced to one equivalent, the reaction gave 4-iodo-3-((E)-4-substituted-1-buten-3-ynyl) isocoumarins in 57- 67 % yields. Other iodinating agents are also introduced in this reaction, similar results were observed when ICl and NIS were employed in this reaction.
author2 Ming-Jung Wu
author_facet Ming-Jung Wu
Tsung-hui Kuo
郭宗輝
author Tsung-hui Kuo
郭宗輝
spellingShingle Tsung-hui Kuo
郭宗輝
Electrophilic Induced Cyclization of Methyl 2-(6-substitued 3-hexen-1,5-diynyl)benzoate :Synthesis ofIsocoumarins
author_sort Tsung-hui Kuo
title Electrophilic Induced Cyclization of Methyl 2-(6-substitued 3-hexen-1,5-diynyl)benzoate :Synthesis ofIsocoumarins
title_short Electrophilic Induced Cyclization of Methyl 2-(6-substitued 3-hexen-1,5-diynyl)benzoate :Synthesis ofIsocoumarins
title_full Electrophilic Induced Cyclization of Methyl 2-(6-substitued 3-hexen-1,5-diynyl)benzoate :Synthesis ofIsocoumarins
title_fullStr Electrophilic Induced Cyclization of Methyl 2-(6-substitued 3-hexen-1,5-diynyl)benzoate :Synthesis ofIsocoumarins
title_full_unstemmed Electrophilic Induced Cyclization of Methyl 2-(6-substitued 3-hexen-1,5-diynyl)benzoate :Synthesis ofIsocoumarins
title_sort electrophilic induced cyclization of methyl 2-(6-substitued 3-hexen-1,5-diynyl)benzoate :synthesis ofisocoumarins
publishDate 2004
url http://ndltd.ncl.edu.tw/handle/84913048776455415353
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AT guōzōnghuī electrophilicinducedcyclizationofmethyl26substitued3hexen15diynylbenzoatesynthesisofisocoumarins
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AT guōzōnghuī 26qǔdàijī3jǐxī15èrguìjīběnjiǎsuānjiǎzhǐdeqīndiànxìngyòudǎohuánhuàyìxūncǎosùdehéchéng
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