The Feasibility Study of Single Tooth Scaffold Construction for Dental Tissue Engineering Using Rapid Prototyping Technology

• Main Authors: Lee Yi-Hsun, 李宜勳
• Other Authors: Jeng-Ywan, Jeng
• Format: Others
• Language: zh-TW
• Published: 2003
• Online Access: http://ndltd.ncl.edu.tw/handle/88674817539373476534

碩士 === 國立臺灣科技大學 === 機械工程系 === 91 === Tissue Engineering uses proliferous cells tissue to cultivate tissue or organ that internal or external the body that we need. It can solve the problem of resource shortage of transplantable organs and the problem of rejection of the immune system of allogeneic organs during transplantation. These three essential factors of tissue engineering, scaffold not only provide cells a multiplied environment but also decide the shape of proliferous tissue. The traditional process of scaffold manufacturing is limited in hard to making a complicated shape and it is difficult to control the size and the distribution of pore that make this basic essential factor a big handicap of development. The purpose of this study is to develop a set of tissue engineering scaffold construction method that combines reverse engineering and rapid prototyping technology. We can use the shape of scaffold and internal structure that we planed before to make scaffold models accurately. We can also use reverse engineering technology to build scaffold CAD models and then to match up sorts of cells and grow the environment that we need to design scaffold internal structure combination. After completely construction of CAD model be cut in several layers with software and output to rapid prototyping machine that use high polymer biomedical materials and then construct every slicing plane layer by layer that we can pile up porous scaffold of complicated shape accurately. This study focused in the fabrication of hard bone of root of single tooth and match up the change of material ingredients and rapid prototyping technology to make local pore and global pore to raise scaffold porosity. Using this system to make scaffold not only the high porosity but also the size of global pore and connectivity are controllable.