Preparation and Verification of Liposomes Suitable for Ultrasound Drug Delivery System

碩士 === 國立臺灣大學 === 電機工程學研究所 === 91 === Combining the characteristic of liposomes with ultrasound , we have built a ultrasound drug delivery system for the utilisation of practical clinical medicine. In this study , by means of the RF signals of ultrasound and the optical measurement of N4-...

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Bibliographic Details
Main Authors: lu, shihjen, 呂適任
Other Authors: 曹建和
Format: Others
Language:zh-TW
Published: 2003
Online Access:http://ndltd.ncl.edu.tw/handle/68767185909875399023
Description
Summary:碩士 === 國立臺灣大學 === 電機工程學研究所 === 91 === Combining the characteristic of liposomes with ultrasound , we have built a ultrasound drug delivery system for the utilisation of practical clinical medicine. In this study , by means of the RF signals of ultrasound and the optical measurement of N4-PLUS COULTER ,we have probed into the preparation , storage and gas-embraced of liposomes, and has looked for liposomes having better physics and chemical properties. It has also demonstrated that we can succeed to embrace gas and verify whether gas is embraced by ultrasound subharmonic signal in the process of preparation of liposomes . Throught changing some components of liposomes ,it has sought a better component ratio of liposomes. In order to consider selection of concentrations of liposomes ,this study has found the relationship between dilution times and signals. By using disperse solution, we get some experiences. In the cold storage of liposomes , liposomes would be better to keep better stability of signal within two weeks. In addition, the result has showed that the signals might be weaken for mixing different disperse solutions to certain extent.