Studies on the Constitutions of the Leaves of Ficus microcarpa

• Main Authors: Lin Huan-You, 林煥祐
• Other Authors: Kuo Yueh-Hsiung
• Format: Others
• Language: en_US
• Published: 2003
• Online Access: http://ndltd.ncl.edu.tw/handle/35587528452446136239

碩士 === 國立臺灣大學 === 化學研究所 === 91 === Abstract The leaves of Ficus microcarpa L. f. were extracted with methanol. The extract was concentrated in vacuo to yield a residue which was suspended in water, and this phase was partitioned with ethyl acetate. The combined ethyl acetate layers afforded a black syrup which was separated by open column chromatography, thin layer chromatography, flash column chromatography, high performance liquid chromatography and recrystallization to afford 34 compounds. Among these compounds, three are new compounds, including one novel skeletons were elucidated. These compounds are classified to 15 triterpenoids, 3 sterols, 7 aromatics, 3 flavonoids, 1 diterpenoid, and 5 others. Three new compounds are shown as follows: 3-Oxo-20a-hydroxy-19(29)-taraxastene(TA1) 3,20-Dioxo-30(20→19)abeolupane(LU4) 3,19,20-Trioxo-19,20-secoursane(UR5) the other compounds are as follows: Betulin(LU1) Betulinic acid(LU2) 3b-Hydroxy-20-oxo-30(20→19)abeolupane(LU3) Erythrodiol(OL1) 3b,15a-Diol-12-oleanen(OL2) 3b-Hydroxyolean-18-en-28-oic acid(OL3) 3b-Hydroxy-11-oxo-12-oleanene(OL4) Squalene(LI1) 3b-Acetoxy-urs-12-ene(UR1) 3b-Hydroxy-11a-methoxyurs-12-ene(UR2) 3b-Hydroxy-11-oxo-12-ursene(UR3) 3b-Hydroxy-9(11),12-ursadiene(UR4) b-Sitosterol(ST1) Stigmast-4-en-3,6-dione(ST2) 6b-Hydroxystigmast-4-en-3-one(ST3) (±)-5,7-Dimethoxy-4''-hydroxyflavan(FL1) Prunetin (FL2) Biochanin A(FL3) Methyl 4-hydroxybenzonate(AR1) 4-Hydroxy-trans-cinnamic acid methyl ester(AR2) 4-Hydroxy-cis-cinnamic acid methyl ester(AR3) 2-Methyl-4-nitrophenol(AR4) 4-Hydroxybenzalaldehyde(AR5) Bis(phenol-4-yl) methane(AR6) 4-Hydroxyacetophenone(AR7) a-Tocopheryl quinone(OT1) a-Tocospiro B(OT2) (10 R)-10-Hydroxypheophytin a(OT3) (10 S)-10-Hydroxypheophytin a(OT4) (132-R)-Pheophytin-a(OT5) Phytol(D1)