Studies on the Synthesis and Biological Activities of Substituted Indoloquinolines

碩士 === 高雄醫學大學 === 藥學研究所碩士在職專班 === 91 === Abstract: Fused nitrogen containing heteroaromatic tetracyclo compounds, such as angular indolo[3,2-c]quinolines and linear indolo[2,3-b]quinolines are known as DNA intercalating agent with anticancer activity. Certain substituted indolo...

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Main Authors: Hsien-Ming Hung, 洪憲明
Other Authors: Cherng-Chyi Tzeng
Format: Others
Language:zh-TW
Published: 2003
Online Access:http://ndltd.ncl.edu.tw/handle/ut7fpz
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spelling ndltd-TW-091KMC015510092019-05-15T20:22:43Z http://ndltd.ncl.edu.tw/handle/ut7fpz Studies on the Synthesis and Biological Activities of Substituted Indoloquinolines 取代的Indoloquinoline類化合物之合成與生物活性研究 Hsien-Ming Hung 洪憲明 碩士 高雄醫學大學 藥學研究所碩士在職專班 91 Abstract: Fused nitrogen containing heteroaromatic tetracyclo compounds, such as angular indolo[3,2-c]quinolines and linear indolo[2,3-b]quinolines are known as DNA intercalating agent with anticancer activity. Certain substituted indoloquinolines, 6-diamine substituted indolo[3,2-c]quinolines, 11-anilinoindolo[2,3-b]quinolines, and 11-methoxyindolo[2,3-b]quinolines have been synthesized and evaluated in vitro against a 3-cell line panel consisting of MCF7 (Breast), NCI-H460 (Lung), and SF-268 (CNS). Cherng-Chyi Tzeng Yeh-Long Chen 曾誠齊 陳義龍 2003 學位論文 ; thesis 57 zh-TW
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language zh-TW
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description 碩士 === 高雄醫學大學 === 藥學研究所碩士在職專班 === 91 === Abstract: Fused nitrogen containing heteroaromatic tetracyclo compounds, such as angular indolo[3,2-c]quinolines and linear indolo[2,3-b]quinolines are known as DNA intercalating agent with anticancer activity. Certain substituted indoloquinolines, 6-diamine substituted indolo[3,2-c]quinolines, 11-anilinoindolo[2,3-b]quinolines, and 11-methoxyindolo[2,3-b]quinolines have been synthesized and evaluated in vitro against a 3-cell line panel consisting of MCF7 (Breast), NCI-H460 (Lung), and SF-268 (CNS).
author2 Cherng-Chyi Tzeng
author_facet Cherng-Chyi Tzeng
Hsien-Ming Hung
洪憲明
author Hsien-Ming Hung
洪憲明
spellingShingle Hsien-Ming Hung
洪憲明
Studies on the Synthesis and Biological Activities of Substituted Indoloquinolines
author_sort Hsien-Ming Hung
title Studies on the Synthesis and Biological Activities of Substituted Indoloquinolines
title_short Studies on the Synthesis and Biological Activities of Substituted Indoloquinolines
title_full Studies on the Synthesis and Biological Activities of Substituted Indoloquinolines
title_fullStr Studies on the Synthesis and Biological Activities of Substituted Indoloquinolines
title_full_unstemmed Studies on the Synthesis and Biological Activities of Substituted Indoloquinolines
title_sort studies on the synthesis and biological activities of substituted indoloquinolines
publishDate 2003
url http://ndltd.ncl.edu.tw/handle/ut7fpz
work_keys_str_mv AT hsienminghung studiesonthesynthesisandbiologicalactivitiesofsubstitutedindoloquinolines
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AT hóngxiànmíng qǔdàideindoloquinolinelèihuàhéwùzhīhéchéngyǔshēngwùhuóxìngyánjiū
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