| Summary: | 碩士 === 中國醫藥學院 === 中西醫結合研究所 === 91 === In the present study, we examined the effects of preemptive analgesia of electroacupuncture (EA) at classical acupuncture points (Yanglingquan and Yinlingquan) on postoperative pain. Eighty patients (ASA class I) undergoing arthroscopic surgery of knee were randomly assigned to four treatment regimens:
Group I (N=20), control group
Group II (N=20), sham-EA (needle intradermal insertion without electrical stimulation)
Group III (N=20), pre-operative EA (pre-op EA; needle insertion with 100 Hz electrical stimulation 30 min prior to anesthesia)
Group IV (N=20), postoperative EA (post-op EA; needle insertion with 100Hz electrical stimulation after the surgery)
All patients received patient-controlled analgesia (PCA) of morphine post-operation. Postoperative pain was evaluated by recording (1) the time of the first required analgesic, (2) the total amount of morphine required by PCA, and (3) Patients’ VAS score, (4) the opioid-related side effect. We found that the time of first analgesic required was 9.90±0.59、22.10±2.26、 47.25±2.47 and 57.30±1.75 minutes in the control, sham-EA, preoperative EA, and postoperative EA groups, respectively. There was significant in statistics by comparing with each other. During the first 24 hours, the total amount of morphine required was 16.25±1.29 mg、11.35±0.87 mg、 6.30±0.88 mg and 4.65±0.64 mg in the control, sham-EA, preoperative EA, and postoperative EA groups, respectively. There was significant in statistics by comparing with each other, except comparing with group III & IV. The incidence of nausea and dizziness during the first 24 hours after surgery was significantly reduced in both pre-op EA and post-op EA groups compared with the control group. We also found that sham-EA exerts a beneficial effect with respect to its pain relieving quality but not the side effect profiles. In conclusion, the present study showed that both pre-op EA and post-op EA group postpone the initial demand for pain control and decrease total PCA dosage within 24 hours. It also demonstrated that the electroacupuncture had the preemptive analgesia on the arthroscopic surgery of knee. And the post-op EA had the better analgesic effect than pre-op EA.
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