Summary: | 碩士 === 國立陽明大學 === 放射醫學科學研究所 === 90 === Abstract
Cerebrovascular disorder has been one of the three most common causes of death. Early diagnosis and immediate treatment are of vital importance to improve prognosis and cut down socioeconomic cost. Among all modalities, including PET and Xenon-CT, capable of measuring cerebral blood flow taken into consideration, transcranial Doppler ultrasonography (TCD) can quantify the flow dynamics but is limited by the lower resolution and poor transcranial penetration of ultrasound. PET and Xenon-CT using ionizing radiation are quite expensive and not popular yet. SPECT perfusion examination is mostly used to semiquantitatively measure the cerebral blood flow. Alternatively magnetic resonance (MR) perfusion examination has been a sophisticated but convenient method developed for one more decades for semiquantitative measurement of cerebral blood flow.
So far, studies using MR perfusion are commonly found in foreign literature but uncommon in Taiwan. This study uses SPECT and MR perfusion examinations simultaneously to semiquantitatively measure the cerebral flow parameters in each patient suffering from cerebrovascular disorder and analyses the results obtained from these two modalities. The aim of our study is to find out the guidelines of applying SPECT and MR perfusion examinations. In addition, we try to do help in modification of treatment planning with proper use of results from these two perfusion modalities. Our results show that the SPECT and MR perfusion examinations correlate well with each other.
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