The effect of the in vivo insulin sensitivity and glucose tolerance during the adolescent growth spurt

• Main Authors: Lin,Che-Hung, 林哲宏
• Other Authors: Kuo,Chia-Hua
• Format: Others
• Language: zh-TW
• Published: 2001
• Online Access: http://ndltd.ncl.edu.tw/handle/31247501420248727566

碩士 === 臺北巿立體育學院 === 運動科學研究所 === 90 === The purpose of the study is to investigate whether the in vivo insulin sensitivity and glucose tolerance is influenced by adolescent growth, the important period of skeletal muscle development. Thirty-six subjects were classified into three categories according to the age of each subject: elementary students（E, N=12）, junior high students（J, N=12）, and senior-high students（S, N=12）. These subjects underwent an overnight fast and the blood samples were collected for baseline measurements. The glucose and insulin concentrations, the blood lipid profile including HDL-C, LDL- C, and total cholesterol, and the hormones that may affect skeletal muscle growth including growth hormone and triiodothyronine, were analyzed in these fasted blood samples. Blood glucose and insulin concentrations of these samples were also measured at 30, 50, and 80 min after a 75-gram of glucose ingestion. We have found that the whole body glucose tolerance was slightly getting lower along the age. When the blood glucose concentration of each subject was normalized by fat-free mass, the S group displayed the highest mean glucose concentration and the E group displayed the lowest mean value among the three age groups (p< 0.05).