Study on Quality of Divided Powders and Impact of Education Program on Pediatric Drug Formulations

• Main Authors: Angela Lin, 林攸美
• Other Authors: Kuang-Yang Hsu
• Format: Others
• Language: zh-TW
• Published: 2002
• Online Access: http://ndltd.ncl.edu.tw/handle/68048229870845691758

碩士 === 台北醫學院 === 藥學研究所 === 90 === Abstract Purpose The purpose of the study was to evaluate： 1. The weight variation of five pediatric prescriptions in divided powders dosage form. 2. The effectiveness of an education intervention on attitudes and knowledge regarding pediatric drug formulations. Methods 1. Five pediatric prescriptions in divided powders dosage form were prepared by pharmacists, nurses and physicians respectively. Weight variation analysis was performed for the preparations, and the coefficients of variation of weight（WCV%）were calculated accordingly as the outcome measurement. 2. Parents of pediatric patients at the inpatient department of Taipei Municipal Wang-Fang Hospital (TMWFH) were enrolled. An education program was conducted individually. Questionnaires containing attitude and knowledge measurements were completed by the parents before and after the education program. Patient's preference to the usage of pediatric formulations was analyzed before the education program. Results 1. The WCV% calculated from all of the divided powders ranged from 4.52% to 51.49%, with a tendency for larger mean weight to have less WCV%. All the mean WCV% of pharmacists was less than that of nurses and physicians. 2. One hundred and two parents of pediatric patients were recruited from March 2002 to April 2002 in TMWFH. After the education program, the attitude scores were significantly improved in the subscale of divided powders and the total scale. The total knowledge scale was significantly increased from 4 to 9 and all the subscale scores were significantly increased (p < 0.05) after the education program. Conclusion This study demonstrates that the divided powders can have considerable problems on dosage uniformity, and the education program provided by the pharmacist is able to cause attitude and knowledge change. This attitude and knowledge change can provide further insight into behavioral change.