| Summary: | 碩士 === 國立臺灣大學 === 環境衛生研究所 === 90 === Heart disease is the leading cause of death in many developed countries and the third most common cause of death in Taiwan. As populations are aging and changing their life styles, acute myocardial infarction (AMI) has become an important public health issue in Taiwan. This study was conducted to investigate factors associated with AMI by exploring the seasonal pattern in population AMI mortality, and measuring the impact of temperature and other risk factors on the onset of this disease in case control study.
First, we analyzed population vital statistics data to determine the seasonal pattern of the AMI mortality and the impact of temperature on deaths from the disease in Northern Taiwan. Second, we investigated the seasonal variation of one-year AMI emergency admission at the National Taiwan University Hospital; third, these AMI cases were further explored for AMI risk factors using a structural questionnaire.
The results obtained from analyzing population mortality data showed that the AMI mortality was season and environmental temperature associated. The average daily mortality of AMI in Northern Taiwan was the highest in winter ( 6.43 deaths/day ) , 1.42 folds higher than that in summer ( 4.52 deaths/day ) . The average daily mortality by month had significant negative correlations with the monthly average temperature, monthly average of the highest daily temperature, and monthly average of the lowest daily temperature. Besides, the AMI mortality had strong negative correlations with the daily average, maximum and minimum temperature.
This study found no significant seasonal fluctuation and environmental temperature association in the emergency AMI admission rate at the National Taiwan University Hospital. Further analysis indicated that smoking, work long hours, excessive fatigue and emotional impulses increased the risk of AMI. And smoking was the most influential factor leading to AMI. History analysis, personal disease history of hypertension, hypercholesterolemia, cerebrovascular disease and diabetes were also risk factors of AMI.
In conclusion, elevated AMI mortality in Northern Taiwan was observed in winter and colder days. However, avoiding smoking, long working hours, excessive fatigue and emotional impulses might be beneficial in reducing the risk of AMI.
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