Summary: | 博士 === 國防醫學院 === 醫學科學研究所 === 90 === Gene therapy is a potential scientific discipline that has already had a profound impact on biomedical science, including basic and clinical eye research. Introduction of therapeutic DNA into various cells of ocular tissue provides a potential strategy to treat various ocular diseases. In addition, The accessibility of the eye and the tendency for some degree of immunologic privilege within the ocular tissues may favor the development of ocular gene therapy. In current time, gene therapy may not only be used to treat inherited eye disease but also be applied to modify or ameliorate acquired diseases such as retinitis pigmentosa and after-cataract. Rapid progress in understanding the molecular basis of clinical ophthalmology will advance the treatment of eye diseases, including the potential for gene therapy. In the coming years, gene therapy will increasingly influence aspects of diagnosis, prognosis, and treatment in clinical ophthalmology. Conventional treatment for both acquired and inherited diseases may be revolutionized by this molecular technology.
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