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• Main Authors: Chih-Chung Wang, 王治中
• Other Authors: none
• Format: Others
• Language: zh-TW
• Published: 2002
• Online Access: http://ndltd.ncl.edu.tw/handle/94938955474269637496

碩士 === 國立中央大學 === 化學研究所 === 90 === The part 1 in this thesis describes a new methodology for the Solid phase synthesis of 1, 3-dihydrobenzoimidazol-2-one containing three points of diversity. This method begins commercially available resin-bond amino group as the source of the first diversity element and employs a combination of solid phase chemistry to introduce the other two. The key step is an intramolecular cyclization and simultaneous traceless cleavage from solid support to give a disubstituted product. The third substituent is introduced in solution by N-alkylation. The part 2 describes the design and synthesis of a series of liquid crystal. All structures were characterized by 1H, 13C NMR, IR spectroscopy and element analysis. The mesomorphic properties exhibited for these compounds were studied by DSC analysis and optical microscope.