| Summary: | 碩士 === 國立成功大學 === 醫學工程研究所碩博士班 === 90 === The purpose of this study was to evaluate the biocompatibilities of nine different surface-processed titanium screws. The types of surface processing included porous, calcium phosphate coating, porous + calcium phosphate coating, and coloring treatment of acid liquids. These implants were inserted into the proximal tibia epiphysis of rabbits and were examined after 12 and 24 weeks with optical microscope (OM) and scanning electron microscope (SEM) to observe the histological morphology and bonding condition between the implant and tissue.
Osseointegration was achieved at 12th and 24th week in all cases except coloring treatment of sulfuric acid. Without mechanical testing, however, interfacial shear strengths were not determined in the study. SEM and OM observations demonstrated calcium phosphate coating implants had the capability of osteoconduction, the same trend was found in coloring treatment of phosphoric acid. In addition to these phenomena, coloring treatment of sulfuric acid could promote resistance of corrosion on the titanium surface but relatively decrease the bioactivity, that is, lower biocompatibility.
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