A Novel Synthesis of 2,5,8,11-Tetrahydro-1,7-dioxabenzo[1,2,4,5]dicycloheptene from Hydroquinone via Claisen Rearrangement and Ring-closing Metathesis Reaction

碩士 === 國立高雄醫學大學 === 藥學研究所碩士在職專班 === 90 === In this study, the diallyl phenyl ether, 1,4-diallyloxybenzene (2), was synthesized from hydroquinone (1) with allyl bromide. 1,4-di- allyloxybenzene (2) was performed the Claisen rearrangement to obtain di-O-allyl phenols, 2,5-diallylhydroquinone (3)....

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Main Authors:	Lin-Hui Kuo, 郭玲惠
Other Authors:	Eng-Chi Wang
Format:	Others
Language:	zh-TW
Published:	2002
Online Access:	http://ndltd.ncl.edu.tw/handle/09894368990548647868

id	ndltd-TW-090KMC01551004
record_format	oai_dc
spelling	ndltd-TW-090KMC015510042016-06-27T16:09:19Z http://ndltd.ncl.edu.tw/handle/09894368990548647868 A Novel Synthesis of 2,5,8,11-Tetrahydro-1,7-dioxabenzo[1,2,4,5]dicycloheptene from Hydroquinone via Claisen Rearrangement and Ring-closing Metathesis Reaction 利用克萊森轉位及新穎的閉環置換反應將對苯二酚合成2,5,8,11-四氫-1,7-雙氧苯[1,2,4,5]雙環庚烯 Lin-Hui Kuo 郭玲惠碩士國立高雄醫學大學藥學研究所碩士在職專班 90 In this study, the diallyl phenyl ether, 1,4-diallyloxybenzene (2), was synthesized from hydroquinone (1) with allyl bromide. 1,4-di- allyloxybenzene (2) was performed the Claisen rearrangement to obtain di-O-allyl phenols, 2,5-diallylhydroquinone (3). Furthermore, compound 3 was performed the allylation again with allyl bromide to give 2,5-diallyl-1,4-diallyloxybenzene (4). Then, 2,5-diallyl-1,4-diallyloxybenzene (4) used the Grubbs catalysts to undergo the ring-closing metathesis reaction, and furnished a novel 7-6-7 tricyclic compound, 2,5,8,11-tetrahydro-1,7-dioxabenzo[1,2,4,5]dicyclo- heptene (5). Eng-Chi Wang 王英基 2002 學位論文 ; thesis 52 zh-TW
collection	NDLTD
language	zh-TW
format	Others
sources	NDLTD
description	碩士 === 國立高雄醫學大學 === 藥學研究所碩士在職專班 === 90 === In this study, the diallyl phenyl ether, 1,4-diallyloxybenzene (2), was synthesized from hydroquinone (1) with allyl bromide. 1,4-di- allyloxybenzene (2) was performed the Claisen rearrangement to obtain di-O-allyl phenols, 2,5-diallylhydroquinone (3). Furthermore, compound 3 was performed the allylation again with allyl bromide to give 2,5-diallyl-1,4-diallyloxybenzene (4). Then, 2,5-diallyl-1,4-diallyloxybenzene (4) used the Grubbs catalysts to undergo the ring-closing metathesis reaction, and furnished a novel 7-6-7 tricyclic compound, 2,5,8,11-tetrahydro-1,7-dioxabenzo[1,2,4,5]dicyclo- heptene (5).
author2	Eng-Chi Wang
author_facet	Eng-Chi Wang Lin-Hui Kuo 郭玲惠
author	Lin-Hui Kuo 郭玲惠
spellingShingle	Lin-Hui Kuo 郭玲惠 A Novel Synthesis of 2,5,8,11-Tetrahydro-1,7-dioxabenzo[1,2,4,5]dicycloheptene from Hydroquinone via Claisen Rearrangement and Ring-closing Metathesis Reaction
author_sort	Lin-Hui Kuo
title	A Novel Synthesis of 2,5,8,11-Tetrahydro-1,7-dioxabenzo[1,2,4,5]dicycloheptene from Hydroquinone via Claisen Rearrangement and Ring-closing Metathesis Reaction
title_short	A Novel Synthesis of 2,5,8,11-Tetrahydro-1,7-dioxabenzo[1,2,4,5]dicycloheptene from Hydroquinone via Claisen Rearrangement and Ring-closing Metathesis Reaction
title_full	A Novel Synthesis of 2,5,8,11-Tetrahydro-1,7-dioxabenzo[1,2,4,5]dicycloheptene from Hydroquinone via Claisen Rearrangement and Ring-closing Metathesis Reaction
title_fullStr	A Novel Synthesis of 2,5,8,11-Tetrahydro-1,7-dioxabenzo[1,2,4,5]dicycloheptene from Hydroquinone via Claisen Rearrangement and Ring-closing Metathesis Reaction
title_full_unstemmed	A Novel Synthesis of 2,5,8,11-Tetrahydro-1,7-dioxabenzo[1,2,4,5]dicycloheptene from Hydroquinone via Claisen Rearrangement and Ring-closing Metathesis Reaction
title_sort	novel synthesis of 2,5,8,11-tetrahydro-1,7-dioxabenzo[1,2,4,5]dicycloheptene from hydroquinone via claisen rearrangement and ring-closing metathesis reaction
publishDate	2002
url	http://ndltd.ncl.edu.tw/handle/09894368990548647868
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A Novel Synthesis of 2,5,8,11-Tetrahydro-1,7-dioxabenzo[1,2,4,5]dicycloheptene from Hydroquinone via Claisen Rearrangement and Ring-closing Metathesis Reaction

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