| Summary: | 碩士 === 國立高雄醫學大學 === 藥學研究所碩士在職專班 === 90 === In this study, the diallyl phenyl ether, 1,4-diallyloxybenzene (2), was synthesized from hydroquinone (1) with allyl bromide. 1,4-di- allyloxybenzene (2) was performed the Claisen rearrangement to obtain di-O-allyl phenols, 2,5-diallylhydroquinone (3).
Furthermore, compound 3 was performed the allylation again with allyl bromide to give 2,5-diallyl-1,4-diallyloxybenzene (4).
Then, 2,5-diallyl-1,4-diallyloxybenzene (4) used the Grubbs catalysts to undergo the ring-closing metathesis reaction, and furnished a novel 7-6-7 tricyclic compound, 2,5,8,11-tetrahydro-1,7-dioxabenzo[1,2,4,5]dicyclo- heptene (5).
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