Design and Synthesis of Anticancer Alkylating Agents of Pyrrolo[2,1-c][1,4]benzodiazepines Containing Amino Group in C Ring

Design and Synthesis of Anticancer Alkylating Agents of Pyrrolo[2,1-c][1,4]benzodiazepines Containing Amino Group in C Ring

碩士 === 高雄醫學大學 === 天然藥物研究所 === 90 === Pyrrolo[2,1-c][1,4]benzodiazepines(PBDs) are a group of potent, naturally occurring antitumor antibiotics produced by Streptomyces species. The cytotoxic and antitumor effects of these compounds are believed to arise from modification of DNA, which lea...

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Bibliographic Details
Main Authors:	Yu-Chen Lin, 林育貞
Other Authors:	Jeh-Jeng Wang
Format:	Others
Language:	zh-TW
Published:	2002
Online Access:	http://ndltd.ncl.edu.tw/handle/79179682309965880076

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