Study of the Disposable Urea Sensor and the Pre-amplifier

• Main Authors: Jia-Chyi Chen, 陳佳琪
• Other Authors: Shen-Kan Hsiung
• Format: Others
• Language: zh-TW
• Published: 2002
• Online Access: http://ndltd.ncl.edu.tw/handle/95108405858980162135

碩士 === 中原大學 === 電子工程研究所 === 90 === In blood the urea concentration can response the unusual absorption of the protein. At the same time, it is also related to the renal function. Therefore, the urea in the blood or urine is the index of the health and the important parameter of the clinical diagnosis. In this study, the extended-gate Field effect transistor of the SnO2/ITO glass was applied to fabricate the disposable urea sensor and to confer with the influence, including the activity of the enzyme, the concentration of the gel, the pH value, the concentration of the phosphate buffer solution…etc. After a series of the experiments, the optimize measurement environment and the best response curves can be realized. The urea sensor of the extended-gate structure can detect the urea concentration from 0.31mg/dl to 80mg/dl, and sensitivity of the linear range is about 169.1mV/pUrea. However, the CMOS standard process of the UMC 0.5um was employed to fabricate the 1.5V low-voltage amplifier. And the characteristic of the amplifier also be measured in this study. Besides, the sensor and the pre-amplifier were also be fabricated by this technique. In this study, two kinds of the structures will be compared, including the separative structure and on a single chip.