| Summary: | 碩士 === 國立臺灣大學 === 環境衛生研究所 === 89 === Abstract
The trend of the prevalence of and mortality from asthma has been in increasing trend among world. Similar pattern in childhood also has been reported in Taipei City. The present study evaluated factors associated with asthma and lung function among adolescent in Taipei. Middle school students-base data in Taipei obtained in 1995-1996 from mass screening survey were examined. A total of 118,138 (91.8%) students participated in the asthma screening and 10,396 randomly students received lung function examination.
Results showed that the prevalence of adolescent asthma decreased as decreased age and was higher for those exercise with less frequency. The prevalence also had significant positive associations with parental education in level and parent assessed air pollution level. Children lived in families with increase burning had lower asthma prevalence. We also found that adolescent lung function was associated with sex, age, height, parent’s education, exercise, and asthma. In general, the average FVC and FEV1 among boys were better than that among girls. However the average FEV1/FVC was reversed. Students'' lung function varied among 12 districts in Taipei. The average highest FVC for boys in Chung Chen District (3.73L) and the lowest in Nan Kag District (3.49L) The corresponding levels for girls were 2.91L in Da An District and 2.78L also in Nan Kag District. The prevalence rates of obstructive ventilatory impairment were lower for older students, but higher for students with asthma, less exercise or drink. The analysis revealed that the risk for students who drank was 8.21 times higher than those who did not drink. The asthmatic students were more likely than nonasthmatic ones to have restrictive ventilatory impairment (odds ratio(OR)=2.56, 95% confidence interval(CI)=1.9-3.28). Asthmatic students were less likely to have this type of impairment than less asthmatic students (OR=0.56, 95%CI=0.47-0.89). We also found negative associations between adolescent lung function and SO2, NO2, CO levels. The FVC decreased 6.1ml as SO2 level increased 1ppb and decreased 3.5ml as NO2 increased 1ppm. In conclusion, environmental air pollution and life style of students can increase the risk of asthma and decreased lung function.
Keywords：asthma, lung function, air pollution
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