| Summary: | 碩士 === 國立臺灣大學 === 化學研究所 === 89 === The whole herb of Bidens bipinnata Linn. was extracted with methanol for three times. The combined extracts were concentrated in vacuo to give a residue,which was subjected to chromatography on silica gel with a gradient solvent system.
Thirty-seven compounds have been isolated and purified. Those include (1) ten long chain fatty alcohols, acids and esters : Tritriacontan-1-ol (1), Tetracosanoic acid (2), Long chain ester (3), Palmitic acid (4), Linolenic acid methyl ester (5), Methyl (9E,11E,13S)-13-Hydroxyoctadeca-9,11-Dienoate (12), Methyl (9Z, 11E, 13S,15Z)-13-hydroxyoctadeca-9,11,15-trienoate (13), (9Z, 11E, 13S,15Z)-13-Hydroxyoctadeca-9,11,15-trienoate (14), 5,7-undecadiyne-1,2,10-triol (27*), (5E)-7,9,11-tridectriyne-5-ene-1,2-diol (28); (2)six steroids: Sitosterol (6), Stigmasterol (7), 6-Hydroxystrgmast-4-en-3-one (8), 6-Hydroxystrgmast-4,22-dien-3-one (9), 3-Hydroxystigmast-5-en-7-one (10), Ergosterol peroxide (11) ; (3) thirteen aromatics : Benzoic acid (15), Cinnamic acid (16), (3E)-4-(3-Methoxy-4-hydroxyphenyl)but-3-en-2-one (17), Methyl trans-sinapate (18), trans-4-Hydroxyphenylbut-3-en-2-one (19), 4-Hydroxybenzaldehyde(20), Methyl ferulate (21), Methyl 4-hydroxycinnamate (22), 4-Hydroxy-3-methoxybenzaldehyde (23), Methyl 3-hydroxy-2-(3-methoxy-4-hydroxyphenyl)-propanoate (24), 7-Phenylhepta-4,6-diyne-2-ol (25), 7-phenylhepta-4,6-diyne-1,2-diol (26), 2,3-dihydroxy-1-(4-hydroxy-3-methoxy-phenyl)-propan-1-one(34); (4)Others are 132-Hydroxy-(132-S)-pheophytin-a (29), (132-S)-pheophytin-a (30), Isocagayanone (31), Isootobanone (32), 8β-Hydroxyotobanone (33), 2,3-dihydroxypropyl hexadecanoate (35), 7,11,15-Trimethyl-3-methylenehexadecan-1,2-diol (36), isobutyric acid 4-acetyl-9a-methyl-7-methylene-2,6-dioxo-decahydro-1,5-dioxa-cyclopenta[f]azulen-8-yl ester (37**).
Among those, 7-phenylhepta-4,6-diyne-2-ol (25), 7-phenylhepta-4,6-diyne-1,2-diol (26), 5,7-undecdiyne-1,2,10-triol (27*), 7,9,11-tridectriyne-5-ene-1,2-diol (28) are special compounds.
*: New compound
**: first isolated from natural source
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