| Summary: | 碩士 === 國立中興大學 === 生物化學研究所 === 89 === Abstract
We isolated and characterized a new compound, M8-4-1, from the methanol extract of Ganoderma amboinense according to an exclusive survey of SDBS (Integrated Spectral Data Base System for Organic Compounds). It was found to be a lanostanoid analog. The structure of M8-4-1 as indicated below, was established by NMR spectroscopy (1H-NMR, COSY, HSQC, HMBC, 13C-NMR), melting point, and chemical methods. The cytotoxic activity assay of M-8-4-1 of Ganoderma amboinense was evaluated against Huh 7 cell line. Therefore, the compound M8-4-1 is cancer cytotoxic potential.
M8-4-1
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