Synthesis of Novel N-Acetyl-N-hydroxy amino Thymidine Derivatives

碩士 === 朝陽科技大學 === 應用化學系碩士班 === 89 === Abstract In this thesis we discuss on the synthesis of compound 42 ,which contains bicyclic deoxynucleose. Two other new compounds, 20 and 21,were obtained during the synthesis process. By applying Mitsunobu...

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Main Authors: CHUNG FEN YU, 鍾芬裕
Other Authors: 楊德芳
Format: Others
Language:zh-TW
Published: 2001
Online Access:http://ndltd.ncl.edu.tw/handle/61563394564179423330
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spelling ndltd-TW-089CYUT05000152015-10-13T12:43:58Z http://ndltd.ncl.edu.tw/handle/61563394564179423330 Synthesis of Novel N-Acetyl-N-hydroxy amino Thymidine Derivatives 羥胺基去氧胸甘衍生物的合成 CHUNG FEN YU 鍾芬裕 碩士 朝陽科技大學 應用化學系碩士班 89 Abstract In this thesis we discuss on the synthesis of compound 42 ,which contains bicyclic deoxynucleose. Two other new compounds, 20 and 21,were obtained during the synthesis process. By applying Mitsunobu method , we have synthesized compound 43. The acetyl group of compound 43 was then hydrolyzed and became compound 42. By cooperating with pharmacologists , we are now evaluating the biological activities of these compounds. We hope that some useful compounds could be successfully derived, which could then be applied to clinical therapies in the near future. 楊德芳 2001 學位論文 ; thesis 82 zh-TW
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language zh-TW
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description 碩士 === 朝陽科技大學 === 應用化學系碩士班 === 89 === Abstract In this thesis we discuss on the synthesis of compound 42 ,which contains bicyclic deoxynucleose. Two other new compounds, 20 and 21,were obtained during the synthesis process. By applying Mitsunobu method , we have synthesized compound 43. The acetyl group of compound 43 was then hydrolyzed and became compound 42. By cooperating with pharmacologists , we are now evaluating the biological activities of these compounds. We hope that some useful compounds could be successfully derived, which could then be applied to clinical therapies in the near future.
author2 楊德芳
author_facet 楊德芳
CHUNG FEN YU
鍾芬裕
author CHUNG FEN YU
鍾芬裕
spellingShingle CHUNG FEN YU
鍾芬裕
Synthesis of Novel N-Acetyl-N-hydroxy amino Thymidine Derivatives
author_sort CHUNG FEN YU
title Synthesis of Novel N-Acetyl-N-hydroxy amino Thymidine Derivatives
title_short Synthesis of Novel N-Acetyl-N-hydroxy amino Thymidine Derivatives
title_full Synthesis of Novel N-Acetyl-N-hydroxy amino Thymidine Derivatives
title_fullStr Synthesis of Novel N-Acetyl-N-hydroxy amino Thymidine Derivatives
title_full_unstemmed Synthesis of Novel N-Acetyl-N-hydroxy amino Thymidine Derivatives
title_sort synthesis of novel n-acetyl-n-hydroxy amino thymidine derivatives
publishDate 2001
url http://ndltd.ncl.edu.tw/handle/61563394564179423330
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