| Summary: | 博士 === 中國醫藥學院 === 中國醫學研究所 === 89 === After reviewing the the ancient classic books , we found the evolution of Sheng-Ji thoughts of sores, which developed from the initial simple stage into the mature and rich expansion stages. Wai Ke Da Cheng Sheng-Ji-San(SJS) was found to be the best external use formula to treat the dermal wounds.
Then, the effectiveness of SJS on treating pressure ulcers has been evaluated. The treated group received routine medical care combined with SJS and the control group received only routine medical care. After 3 weeks, the treated group gained a higher reduction ratio of surface area and effective ratio and only the use of SJS is correlated with the effectiveness after analysis. SJS promote the healing of pressure ulcers successfully.
According to the correlationship between ischemia, post-ischemic reperfusion injury and the pressure ulcers, we tried to investigate the anti-oxidative effect of SJS. The result showed that SJS effectively scavenge the superoxide anion produced by Xanthine/ Xanthine oxidase and also inhibit the lipid peroxidation induced by ferrous chloride. I Acacia catechu inhibit hydroperoxide, hypochloride and superoxide produced by stimulated human white cells. It’s contributory to understanding the mechanism of SJS to accelerate the healing of pressure ulcers.
Our series studies convinced that SJS is an effective prescription in promoting the healing of pressure ulcers both theoretically and clinically.
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