Complex Segregation Analysis of Aborigines Gouty Families in Taiwan

碩士 === 高雄醫學大學 === 醫學研究所 === 88 === Complex segregation analyses were conducted on families of gout probands to delineate the mode of the inheritance. The probands were ascertained from the persons we had visited by door to door and the gout disease had been identified by a practical doctor. The anal...

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Main Authors: Feng Yu-Ping, 馮毓屏
Other Authors: ko Ying-Chin
Format: Others
Language:zh-TW
Published: 2000
Online Access:http://ndltd.ncl.edu.tw/handle/46961445695777504042
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spelling ndltd-TW-088KMC005340322015-10-13T10:56:27Z http://ndltd.ncl.edu.tw/handle/46961445695777504042 Complex Segregation Analysis of Aborigines Gouty Families in Taiwan 台灣原住民痛風家庭複雜分離分析 Feng Yu-Ping 馮毓屏 碩士 高雄醫學大學 醫學研究所 88 Complex segregation analyses were conducted on families of gout probands to delineate the mode of the inheritance. The probands were ascertained from the persons we had visited by door to door and the gout disease had been identified by a practical doctor. The analyses were based on data from 64 aboriginal families with 945 individuals living in Taiwan, and were performed by using the REGTL (Release 2.2) program of the SAGE (version 3.0) package. The gout information of adults was provided by themselves and that of children was from their parents. We used sex and age to adjust covariates. A single locus model fitted the data well, but none of the Mendelian models (recessive, dominant, and arbitrary) could be distinguished. The no-parent-offspring-transmission hypothesis was rejected. However, when we split the data into early-onset and late-onset, both Mendelian and environmental hypotheses relatively were rejected. ko Ying-Chin 葛應欽 2000 學位論文 ; thesis 63 zh-TW
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language zh-TW
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description 碩士 === 高雄醫學大學 === 醫學研究所 === 88 === Complex segregation analyses were conducted on families of gout probands to delineate the mode of the inheritance. The probands were ascertained from the persons we had visited by door to door and the gout disease had been identified by a practical doctor. The analyses were based on data from 64 aboriginal families with 945 individuals living in Taiwan, and were performed by using the REGTL (Release 2.2) program of the SAGE (version 3.0) package. The gout information of adults was provided by themselves and that of children was from their parents. We used sex and age to adjust covariates. A single locus model fitted the data well, but none of the Mendelian models (recessive, dominant, and arbitrary) could be distinguished. The no-parent-offspring-transmission hypothesis was rejected. However, when we split the data into early-onset and late-onset, both Mendelian and environmental hypotheses relatively were rejected.
author2 ko Ying-Chin
author_facet ko Ying-Chin
Feng Yu-Ping
馮毓屏
author Feng Yu-Ping
馮毓屏
spellingShingle Feng Yu-Ping
馮毓屏
Complex Segregation Analysis of Aborigines Gouty Families in Taiwan
author_sort Feng Yu-Ping
title Complex Segregation Analysis of Aborigines Gouty Families in Taiwan
title_short Complex Segregation Analysis of Aborigines Gouty Families in Taiwan
title_full Complex Segregation Analysis of Aborigines Gouty Families in Taiwan
title_fullStr Complex Segregation Analysis of Aborigines Gouty Families in Taiwan
title_full_unstemmed Complex Segregation Analysis of Aborigines Gouty Families in Taiwan
title_sort complex segregation analysis of aborigines gouty families in taiwan
publishDate 2000
url http://ndltd.ncl.edu.tw/handle/46961445695777504042
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