Complex Segregation Analysis of Aborigines Gouty Families in Taiwan
碩士 === 高雄醫學大學 === 醫學研究所 === 88 === Complex segregation analyses were conducted on families of gout probands to delineate the mode of the inheritance. The probands were ascertained from the persons we had visited by door to door and the gout disease had been identified by a practical doctor. The anal...
Main Authors: | , |
---|---|
Other Authors: | |
Format: | Others |
Language: | zh-TW |
Published: |
2000
|
Online Access: | http://ndltd.ncl.edu.tw/handle/46961445695777504042 |
id |
ndltd-TW-088KMC00534032 |
---|---|
record_format |
oai_dc |
spelling |
ndltd-TW-088KMC005340322015-10-13T10:56:27Z http://ndltd.ncl.edu.tw/handle/46961445695777504042 Complex Segregation Analysis of Aborigines Gouty Families in Taiwan 台灣原住民痛風家庭複雜分離分析 Feng Yu-Ping 馮毓屏 碩士 高雄醫學大學 醫學研究所 88 Complex segregation analyses were conducted on families of gout probands to delineate the mode of the inheritance. The probands were ascertained from the persons we had visited by door to door and the gout disease had been identified by a practical doctor. The analyses were based on data from 64 aboriginal families with 945 individuals living in Taiwan, and were performed by using the REGTL (Release 2.2) program of the SAGE (version 3.0) package. The gout information of adults was provided by themselves and that of children was from their parents. We used sex and age to adjust covariates. A single locus model fitted the data well, but none of the Mendelian models (recessive, dominant, and arbitrary) could be distinguished. The no-parent-offspring-transmission hypothesis was rejected. However, when we split the data into early-onset and late-onset, both Mendelian and environmental hypotheses relatively were rejected. ko Ying-Chin 葛應欽 2000 學位論文 ; thesis 63 zh-TW |
collection |
NDLTD |
language |
zh-TW |
format |
Others
|
sources |
NDLTD |
description |
碩士 === 高雄醫學大學 === 醫學研究所 === 88 === Complex segregation analyses were conducted on families of gout probands to delineate the mode of the inheritance. The probands were ascertained from the persons we had visited by door to door and the gout disease had been identified by a practical doctor. The analyses were based on data from 64 aboriginal families with 945 individuals living in Taiwan, and were performed by using the REGTL (Release 2.2) program of the SAGE (version 3.0) package. The gout information of adults was provided by themselves and that of children was from their parents. We used sex and age to adjust covariates. A single locus model fitted the data well, but none of the Mendelian models (recessive, dominant, and arbitrary) could be distinguished. The no-parent-offspring-transmission hypothesis was rejected. However, when we split the data into early-onset and late-onset, both Mendelian and environmental hypotheses relatively were rejected.
|
author2 |
ko Ying-Chin |
author_facet |
ko Ying-Chin Feng Yu-Ping 馮毓屏 |
author |
Feng Yu-Ping 馮毓屏 |
spellingShingle |
Feng Yu-Ping 馮毓屏 Complex Segregation Analysis of Aborigines Gouty Families in Taiwan |
author_sort |
Feng Yu-Ping |
title |
Complex Segregation Analysis of Aborigines Gouty Families in Taiwan |
title_short |
Complex Segregation Analysis of Aborigines Gouty Families in Taiwan |
title_full |
Complex Segregation Analysis of Aborigines Gouty Families in Taiwan |
title_fullStr |
Complex Segregation Analysis of Aborigines Gouty Families in Taiwan |
title_full_unstemmed |
Complex Segregation Analysis of Aborigines Gouty Families in Taiwan |
title_sort |
complex segregation analysis of aborigines gouty families in taiwan |
publishDate |
2000 |
url |
http://ndltd.ncl.edu.tw/handle/46961445695777504042 |
work_keys_str_mv |
AT fengyuping complexsegregationanalysisofaboriginesgoutyfamiliesintaiwan AT féngyùpíng complexsegregationanalysisofaboriginesgoutyfamiliesintaiwan AT fengyuping táiwānyuánzhùmíntòngfēngjiātíngfùzáfēnlífēnxī AT féngyùpíng táiwānyuánzhùmíntòngfēngjiātíngfùzáfēnlífēnxī |
_version_ |
1716833509610356736 |